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The blood glucose-lowering effect of oral hypoglycaemic medicinal products decreases in many patients over timeThis may be due to progression of the severity of the diabetes or to diminished responsiveness to the medicinal productThis phenomenon is known as secondary failureto distinguish it from primary failurewhere the medicinal product is ineffective in an individual patient when first givenAdjustment of dose and adherence to diet and exercise should be assessed before classifying a patient as a secondary failure.

Check the labels on all your medicinessuch as cough-and-cold productscarefullySome products may contain sugar or alcohol and may affect your blood sugarAsk your doctor or pharmacist about using these products safely.

It is unknown if this drug passes into breast milkBecause of possible risk to the infantbreast-feeding while using this drug is not recommendedConsult your doctor before breast-feeding.

Repaglinide should only be prescribed if poor blood glucose control and symptoms of diabetes persist despite adequate attempts at dietingexercise and weight reduction.

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